Basic Organization Information
Alliance for Lupus Research, Inc.
- Also Known As:
- Physical Address:
New York, NY
- Web URL:
- NTEE Category:
H Medical Research
H12 Fund Raising and/or Fund Distribution
H Medical Research
H01 Alliance/Advocacy Organizations
H Medical Research
H80 Specifically Named Diseases Research
- Ruling Year:
- How This Organization Is Funded:
Public support - $8,871,788
Quasi Endowment Investment Income - $4,755,216
The mission of the Alliance for Lupus Research is to prevent, treat and cure Systemic Lupus Erythematosus through bio-medical research.
Lupus Research Grants
- Population Served:
Females, all ages or age unspecified
Ethnic/Racial Minorities -- General
The mission of the Alliance for Lupus Research (ALR) is to find better treatments and ultimately prevent and cure Systemic Lupus Erythematosus (SLE or lupus), a debilitating autoimmune disease, through medical research. To accomplish this mission, the ALR engages in active grant making management, working hand-in-hand with investigators to guide and drive the research process.
ALR’s unique funding model supports promising research efforts with the goal of improving the lives of people with lupus in the near future. Through a competitive peer-review process and an innovative venture-capitalist approach, projects by the ALR aim to translate results from the research bench to the bedside. Because the ALR’s board of directors pays for administrative and fundraising expenses, 100% of all other contributions goes to support lupus research programs like SLEGEN.
Program Long-Term Success:
Since its inception, the ALR has committed over $55 million to fund lupus research projects. We want to find a cure for lupus but in the meantime the long-term success will be for new treatments to come about for lupus patients.
Program Short-Term Success:
The ALR's approach to lupus research has made great progress toward understanding lupus, and we are closer than ever to finding new treatments. Several promising potential drugs are now in clinical trials - a number of which have resulted directly from ALR funding.
Program Success Monitored by:
Scientific Advisory Board
Program Success Examples:
In 2005, the ALR launched a global consortium of lupus researchers. Members of the International SLE Genetics (SLEGEN) Consortium pooled their resources and intellects, determined to find the genes responsible for lupus. Researchers uncovered robust evidence linking 13 genetic candidates to lupus. The three-year project was supported by $2.5 million in funding from the ALR.
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Impact Summary from the Nonprofit
We believe the solution to lupus is a significant increase in biomedical research focused on new treatments, prevention, and a cure.
ALR uses a multi-level review system to ensure that it supports only the finest and most relevant lupus research projects. Applications for funding are rigorously scrutinized through a system called peer-review, in which an individually tailored panel of scientific experts reviews and ranks each research proposal. Then the ALR’s Scientific Advisory Board provides a second level of scrutiny before making funding recommendations to ALR’s Board of Directors, whose members function as final, non-scientist reviewers.
Since its founding, ALR has given more money to lupus research than any non-governmental agency in the world; to date over $81 million has been committed.
Because our Board of Directors funds all administrative and fundraising expenses, one hundred percent of all donations from the public, and the proceeds of our signature grassroots fundraising program, Walk with Us to Cure Lupus, go directly to support research programs.
Great progress is being made as a result of this unprecedented focus on biomedical research. ALR-funded scientists are identifying genes that may predispose individuals to lupus. They are unraveling the ways that the immune system causes the tissue and organ damage so characteristic of the disease. New medications are being designed and tested so that the disease and its complications can be treated more safely and effectively, and perhaps even prevented. New approaches to diagnose and monitor the disease are also being developed.