Cancer Research Fund of the Damon Runyon - Walter Winchell Foundation
Funding brave and bold.
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Programs and results
What we aim to solve
Since our founding in 1946, the Damon Runyon Cancer Research Foundation has invested nearly $450M to fund nearly 4,000 young scientists and their innovative ideas from bench to bedside toward our mission to end all forms of cancer. Through the guidance of our unparalleled scientific committees, we find the most promising early career scientists, support their high-risk, high-reward research, and provide them a network of peers and mentors that enables them to make critical breakthroughs when other, traditional funding sources will not. Today’s scientists typically do not receive independent support from the federal government (the primary funder of research in the US) until age 42. We believe that these young investigators are the key to transformative developments in cancer prevention, diagnosis, and treatment. Our foundation aims to free them from the constraints of "safe bet funding" and provide them with the support needed to pursue their brave and bold ideas.
Our programs
What are the organization's current programs, how do they measure success, and who do the programs serve?
Program Overview
Since our founding in 1946, promising scientists identified and supported by Damon Runyon have made breakthrough discoveries that have transformed our understanding of cancer and developed new approaches to its prevention, diagnosis, and treatment. Damon Runyon offers eight programs aimed at encouraging and advancing the work of early career cancer researchers with the highest promise. Each program is overseen by a separate committee of renowned scientists who select our award recipients and is designed to address a need or fill a gap in cancer research funding. Our rigorous grantmaking process seeks emerging talent with bold innovative ideas, who are willing to take risks and are not daunted by the most complex scientific challenges. As of 2023, 13 former Damon Runyon scientists have received the Nobel Prize for their groundbreaking research and hundreds more have been bestowed the highest accolades for their contributions.
Damon Runyon Fellowship Award
The Damon Runyon Fellowship Award provides $300,000 of funding paid over 4 years to approximately 36 postdoctoral scientists annually that are completing their training and expanding their scientific expertise under the mentorship of a recognized scientific leader. To encourage physician-scientists to pursue a career in cancer research, awardees may also apply for assistance with medical school loan repayment of up to $100,000 on qualifying loans. At the end of their fellowships, the most exceptional researchers in this award program are eligible to receive the Dale F. Frey Award for Breakthrough Scientists, which includes an additional $100,000 of support to further catalyze their research and careers.
Damon Runyon Dale F. Frey Award for Breakthrough Scientists
At the end of the Damon Runyon Fellowship, there are often a select few researchers who have greatly exceeded the Foundation’s highest expectations. These spectacular young scientists are the most likely to make paradigm-shifting breakthroughs that transform the way we prevent, diagnose, and treat cancer. To catapult their research careers—and their impact on cancer—the Foundation makes an additional $100,000 investment over a two-year period in these exceptional individuals by selecting them as recipients of the Damon Runyon-Dale F. Frey Award for Breakthrough Scientists (5-6 awardees annually). In doing so, the Foundation provides additional financial support to enable these scientists to continue the pursuit of bold and innovative ideas, accelerates the path to independence, and encourages a continued career in cancer research.
Damon Runyon Clinical Investigator Award
The Damon Runyon Clinical Investigator Award was developed to accelerate the process of moving discoveries from bench-to-bedside by identifying the best early career physician-scientists and supporting their patient-oriented, translational research. In providing outstanding young physicians with the resources and training structure essential to becoming successful clinical investigators, this innovative program aims to increase the number of physicians who can seamlessly move between the laboratory and the clinic in search of breakthrough diagnostics and treatments. The Clinical Investigator Award provides each recipient $600,000 over three years. Recipients are also offered the opportunity to retire up to $100,000 of their medical school debt, recognizing the incredible financial burden physicians incur during their training. Furthermore, each awardee has the opportunity to apply for two additional years of funding ($400,000 over two years).
Damon Runyon-Rachleff Innovation Award
The Damon Runyon-Rachleff Innovation Award supports the next generation of exceptionally creative thinkers with high-risk, high-reward ideas that have the potential to significantly impact our understanding of and/or approaches to the prevention, diagnosis, or treatment of cancer but lack sufficient preliminary data to obtain traditional funding. The Innovation Award is specifically designed to provide funding to early career independent researchers who have an innovative new idea, not incremental advances. The research supported by the award must be novel, exceptionally creative and, if successful, have the strong potential for high impact in the cancer field. The Stage 1 award is awarded to 4-6 scientists annually, for two years at $200,000 per year ($400,000 total). The Stage 2 award, supporting years three and four (an additional $400,000), is granted to those awardees who demonstrate significant progress on their proposed research during years one and two of the award.
Damon Runyon Physician-Scientist Training Award
The Damon Runyon Physician-Scientist Training Award supports and encourages outstanding physicians to pursue cancer research careers by providing them with the opportunity for a protected research experience under the training of a highly qualified and gifted mentor. The four-year award provides $460,000 of funding to 3-5 physicians annually. Awardees may also apply for assistance with medical school loan repayment of up to $100,000 on qualifying loans.
Damon Runyon Quantitative Biology Fellowship Award
The Damon Runyon Quantitative Biology Fellowship Award program is designed to encourage quantitative scientists (trained in fields such as mathematics, computer science, physics, engineering, or related) to pursue research careers in computational biology under the joint mentorship of leaders in both computational science (“dry lab”) and cancer biology (“wet lab”). By investing in this area, Damon Runyon brings additional attention to the importance of these specially trained scientists for making meaningful progress in cancer biology. This three-year award provides $240,000 of funding to 3-5 scientists annually. Awardees may also apply for assistance with medical school loan repayment of up to $100,000 on qualifying loans.
Damon Runyon-St. Jude Pediatric Cancer Research Fellowship Award
The Damon Runyon-St. Jude Pediatric Cancer Research Fellowship Award provides funding to early career scientists conducting research with the potential to significantly impact the prevention, diagnosis, or treatment of one or more pediatric cancers. We aim to identify and support the future breakthrough scientists working on addressing difficult questions in pediatric cancer research.
Damon Runyon Scholars Program for Advancing Research and Knowledge (SPARK)
Damon Runyon wants to ensure that the best young college students and recent college graduates are encouraged to pursue rigorous scientific education and to commit their talents to tackling longstanding challenges in cancer research. We recognize that these emerging scientists will come from a variety of backgrounds. To provide those with the talent, passion, curiosity, and determination to pursue a career in cancer research with an opportunity to do so, we are introducing the Damon Runyon Scholars Program for Advancing Research and Knowledge (SPARK).
Where we work
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Our results
How does this organization measure their results? It's a hard question but an important one.
Number of scientists supported via Covid relief/extension funding
This metric is no longer tracked.Totals By Year
Population(s) Served
Researchers
Related Program
Damon Runyon Fellowship Award
Type of Metric
Output - describing our activities and reach
Direction of Success
Decreasing
Context Notes
Scientists in the final year of their awards were given the opportunity to apply for up to 6 months of additional funding to support their research that was impacted by Covid related shutdowns.
Average grant amount
This metric is no longer tracked.Totals By Year
Population(s) Served
Researchers
Type of Metric
Output - describing our activities and reach
Direction of Success
Increasing
Context Notes
Because of recent Fellowship stipend increases, current classes of awardees are receiving annual funding above the initial amounts promised.
Number of new awards given each year
This metric is no longer tracked.Totals By Year
Population(s) Served
Researchers
Type of Metric
Output - describing our activities and reach
Direction of Success
Increasing
Goals & Strategy
Learn about the organization's key goals, strategies, capabilities, and progress.
Charting impact
Four powerful questions that require reflection about what really matters - results.
What is the organization aiming to accomplish?
We believe that encouraging emerging young talent to pursue their brave and bold ideas is the best strategy to achieve cancer research innovations. Our eight programs span translational research (Damon Runyon Clinical Investigator Award and Damon Runyon Physician-Scientist Training Award), training of tomorrow’s scientific leaders (Damon Runyon Fellowship Award, Damon Runyon Quantitative Biology Fellowship Award, Damon Runyon-Dale F. Frey Award for Breakthrough Scientists, Damon Runyon-St. Jude Pediatric Cancer Research Fellowship Award, and Damon Runyon SPARK program), and cutting-edge innovation (Damon Runyon Rachleff Innovation Award).
What are the organization's key strategies for making this happen?
Damon Runyon uniquely identifies the most promising scientists early in their careers and provides them with the freedom and resources to pursue the next breakthroughs in cancer research. We foster new generations of elite scientists and fill gaps in traditional research funding that threaten future breakthroughs. Our strategy ensures that the most brilliant, creative, and audacious scientific minds are singularly focused on this goal.
What are the organization's capabilities for doing this?
Through our eight award programs, Damon Runyon scientists receive guaranteed financial support, allowing them to focus on research, not grant-writing. Just as important, our awards offer them the freedom to follow their own ideas, explore new paths, and take risks. Our prestigious endorsement attracts further funding, advances their careers, and accelerates their research. Additionally, we offer to retire up to $100,000 in medical school debt for those physician scientists who are pursuing cancer research.
What have they accomplished so far and what's next?
Since our founding in 1946, promising scientists identified and supported by Damon Runyon have gone on to make breakthrough discoveries that have transformed our understanding of cancer and develop new approaches to prevention, diagnosis, and treatment of all forms of this disease. Damon Runyon scientists have:
• Been front and center in deciphering the genetic drivers of cancer, including identifying the first cancer-causing gene and leadership in the national Human Genome Atlas project to identify the key genetic drivers of a broad range of cancers
• Pioneered the study of the immune system, which has led to the current success of cancer immunotherapies
• Developed many of the technologies used today to study cancer, such as tools to edit the genome (CRISPR Cas9) and study cancer at the single cell level
• Proved the link between cigarette smoking and cancer
• First cured a solid tumor with chemotherapy
• First cured a patient with Stage IV melanoma using only immunotherapy
• Were directly involved in the development and approval of new targeted therapies such as Herceptin, Erbitux, Yervoy, and Zelboraf
• Have founded innovative biotech companies, such as Juno Therapeutics, Syros Pharmacueticals, Sunesis Pharmaceuticals, and others
• Have been awarded the highest honors in science, including 13 Nobel Prizes as of 2024
Damon Runyon has invested nearly $450 million in nearly 4,000 exceptional scientists. To this day, we support the next generation of leaders: emerging talent with unique insights, drive, and boundless vision. We will not stop until we have the tools to prevent or cure all cancers.
How we listen
Seeking feedback from people served makes programs more responsive and effective. Here’s how this organization is listening.
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How is your organization using feedback from the people you serve?
To make fundamental changes to our programs and/or operations, To inform the development of new programs/projects, To identify where we are less inclusive or equitable across demographic groups, To strengthen relationships with the people we serve, To understand people's needs and how we can help them achieve their goals
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Which of the following feedback practices does your organization routinely carry out?
We collect feedback from the people we serve at least annually, We take steps to get feedback from marginalized or under-represented people, We aim to collect feedback from as many people we serve as possible, We take steps to ensure people feel comfortable being honest with us, We look for patterns in feedback based on demographics (e.g., race, age, gender, etc.), We look for patterns in feedback based on people’s interactions with us (e.g., site, frequency of service, etc.), We engage the people who provide feedback in looking for ways we can improve in response, We act on the feedback we receive, We tell the people who gave us feedback how we acted on their feedback, We ask the people who gave us feedback how well they think we responded
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What challenges does the organization face when collecting feedback?
We don't have any major challenges to collecting feedback
Financials
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Operations
The people, governance practices, and partners that make the organization tick.
Connect with nonprofit leaders
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- Analyze a variety of pre-calculated financial metrics
- Access beautifully interactive analysis and comparison tools
- Compare nonprofit financials to similar organizations
Want to see how you can enhance your nonprofit research and unlock more insights? Learn More about GuideStar Pro.
Connect with nonprofit leaders
SubscribeBuild relationships with key people who manage and lead nonprofit organizations with GuideStar Pro. Try a low commitment monthly plan today.
- Analyze a variety of pre-calculated financial metrics
- Access beautifully interactive analysis and comparison tools
- Compare nonprofit financials to similar organizations
Want to see how you can enhance your nonprofit research and unlock more insights? Learn More about GuideStar Pro.
Cancer Research Fund of the Damon Runyon - Walter Winchell Foundation
Board of directorsas of 09/06/2024
Mr. Andy Rachleff
Wealthfront
Term: 2024 -
Carlos L. Arteaga, MD
Director, Harold C. Simmons Comprehensive Cancer Center; Associate Dean, Oncology Programs; Professor, Medicine; Lisa K. Simmons Distinguished Chair in Comprehensive Oncology, University of Texas Southwestern Medical Center, Dallas, TX
David M. Beirne
General Partner, X10 Capital, San Francisco, CA
Steven J. Burakoff, MD
Dean for Cancer Innovation, Director Emeritus, The Tisch Cancer Institute; Chief, Division of Pediatric Hematology and Oncology; Lillian and Henry M. Stratton Professor of Cancer Medicine; Professor of Medicine, Professor of Oncological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
Robyn Coles
President, TRATE Properties, LLC, New York, NY
Gary E. Erlbaum
President, Greentree Properties, Ardmore, PA
Buck French
General Partner, X10 Capital, San Francisco, CA
Elaine Fuchs, PhD
Laboratory Head, Laboratory of Mammalian Cell Biology & Development, Rebecca C. Lancefield Professor, The Rockefeller University; Howard Hughes Medical Institute Investigator, New York, NY
Levi A. Garraway, MD, PhD
Executive Vice President; Head of Global Product Development; Chief Medical Officer, Genentech/Roche, South San Francisco, CA
Richard B. Gaynor, MD
President and Chief of Research and Development, BioNTech US, Inc., Cambridge, MA
Todd R. Golub, MD
Director and Founding Core Institute Member, Broad Institute of MIT and Harvard; Charles A. Dana Investigator in Human Cancer Genetics, Dana-Farber Cancer Institute; Professor of Pediatrics at Harvard Medical School Cambridge, MA
Michael L. Gordon
New York, NY
Scott Greenstein
President and Chief Content Officer, SiriusXM, New York, NY
Morana Jovan-Embiricos, PhD
Managing Partner, F2 Capital Ventures, LLP, London, UK
William G. Kaelin, Jr., MD
Sidney Farber Professor of Medicine, Dana-Farber Cancer Institute and Harvard Medical School, Howard Hughes Medical Institute Investigator, Boston, MA
Steven A. Kandarian
Chairman, President and CEO (retired), Metlife, Inc., North Palm Beach, FL
Noah Knauf
General Partner, Bond Capital, San Francisco, CA
Gabrielle Layton, PhD
Palo Alto, CA
David G. Marshall
Chairman and CEO, Amerimar Realty Company, Philadelphia, PA
Richard W. Meier
Director, The Bakewell Foundation, St. Louis, MO
Sanford W. Morhouse, Esq.
Of Counsel, Schulte Roth & Zabel LLP, New York, NY
John H. Myers
President (retired) GE Asset Management, Fairfield, CT
Richard J. O'Reilly, MD
Claire L. Tow Chair in Pediatric Oncology Research, Memorial Sloan Kettering Cancer Center, New York, NY
Michael V. Seiden, MD, PhD
Chief Executive Officer & Co-Founder, Gladius Therapeutics, The Woodlands, TX
Karen D. Seitz
Founder and Managing Director, Fusion Partners Global, LLC, New York, NY
Nancy Simonian, MD
Chief Executive Officer (Retired), Syros Pharmaceuticals, Inc., Cambridge, MA
Cynthia F. Sulzberger
Wellington, FL
Judy Swanson
Hillsborough, CA
Peter Van Camp
Executive Chairman, Equinix, Inc., Redwood City, CA
James A. Wells, PhD
Professor, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA
Deborah J. Coleman
Boston, MA
Amoolya Singh, PhD
Senior Vice President Data Science; Chief Scientific Officer, Grail, Menlo Park, CA
Melissa L. Cohn
Regional Vice President, William Raveis Mortgage, LLC, Delray Beach, FL
Erica Evans Gioffre
Management Committee Member, Hirtle, Callaghan, & Company, West Conshohoken, PA
David A. Gordon, PhD
Strategist, Bridgewater Associates, Westport, CT
Gerald M. Marshall
President & CEO, Netrality Data Centers; Chairman & CEO, Amerimar Enterprises, Inc., Miami Beach, FL
Joseph Pearlberg, MD, PhD
Vice President of Scientific Affairs of the Therapeutics Team, Deerfield Management Company, New York, NY
Lori J. Pierce, MD
Professor, Radiation Oncology; Vice Provost for Academic and Faculty Affairs, University of Michigan, Ann Arbor, MI
Adam R. Schwartz
Co-Managing Partner, TPG Angelo Gordon, New York, NY
Board leadership practices
GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.
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Board orientation and education
Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Yes -
CEO oversight
Has the board conducted a formal, written assessment of the chief executive within the past year ? Yes -
Ethics and transparency
Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes -
Board composition
Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Yes -
Board performance
Has the board conducted a formal, written self-assessment of its performance within the past three years? No
Organizational demographics
Who works and leads organizations that serve our diverse communities? Candid partnered with CHANGE Philanthropy on this demographic section.
Leadership
The organization's leader identifies as:
Race & ethnicity
No data
Gender identity
No data
Transgender Identity
No data
Sexual orientation
No data
Disability
No data
Equity strategies
Last updated: 05/11/2022GuideStar partnered with Equity in the Center - an organization that works to shift mindsets, practices, and systems to increase racial equity - to create this section. Learn more
- We review compensation data across the organization (and by staff levels) to identify disparities by race.
- We ask team members to identify racial disparities in their programs and / or portfolios.
- We employ non-traditional ways of gathering feedback on programs and trainings, which may include interviews, roundtables, and external reviews with/by community stakeholders.
- We have long-term strategic plans and measurable goals for creating a culture such that one’s race identity has no influence on how they fare within the organization.
- We seek individuals from various race backgrounds for board and executive director/CEO positions within our organization.
- We help senior leadership understand how to be inclusive leaders with learning approaches that emphasize reflection, iteration, and adaptability.
- We engage everyone, from the board to staff levels of the organization, in race equity work and ensure that individuals understand their roles in creating culture such that one’s race identity has no influence on how they fare within the organization.