NeuroSpring
Catalyst for Neuroscientific Breakthroughs
Programs and results
What we aim to solve
NeuroSpring is advancing research in the neurosciences for the purpose of creating new treatments for neurological conditions and training the next generation of scientists and inventors. Our current focus is on bringing treatment to patients with neurological emergencies in the ambulance, which involves supporting the development of (i) a diagnostic capabilities to identify patients with neurological emergencies in the ambulance and (ii) a non-invasive, portable medical therapies to treat those patients.
Our programs
What are the organization's current programs, how do they measure success, and who do the programs serve?
Immediate Treatment of Neurological Emergencies in the Ambulance
Facial nerve stimulation is a novel, non-invasive medical therapy that reverses the loss of brain blood flow (brain ischemia) in ischemic stroke and traumatic brain injury. Facial nerve stimulation immediately restores blood flow to the brain by activating a nerve that dilates brain arteries. Doing so will save injured brain tissue and prevent neurological damage that cripples and kills millions worldwide each year.
The Haptoglobin-Vasospasm Project
Cerebral artery vasospasm is a constriction of brain arteries developing several days after subarachnoid hemorrhage. Vasospasm is the primary cause of morbidity and mortality in subarachnoid hemorrhage patients who survive the initial hemorrhage. Support by an American Heart Association grant, NeuroSpring's research found a protein in the blood - haptoglobin - to be the strongest risk factor for predicting the development of vasospasm in subarachnoid hemorrhage patients.
The Ouabain-Pseudotumor Project
Pseudotumor cerebri (also known as idiopathic intracranial hypertension) is a headache condition that often damages the vision. Caused by an increase in pressure inside the skull, pseudotumor was previous not known to have a cause. With support from the National Headache Foundation, NeuroSpring was first to discover a link between levels of the steroid, ouabain, and pseudotumor cerebri.
The Glucocorticoid - Traumatic Brain Injury Project
A family of steroids known as glucocorticoids has often been studied as a possible therapy for traumatic brain injury patients, but with conflicting and confusing results. NeuroSpring evaluated the literature, and its findings suggest that glucocorticoids may be effective but only in certain types of traumatic brain injury patients.
The Insula Stroke Project
Previous research has suggested that stroke in a certain part of the brain called the insula cortex are particularly dangerous because it affects cardiac function. NeuroSpring's research indicates that the association between stroke in the insula and poor outcomes is not so straightforward as previously believed.
Diagnosing Neurological Emergencies in the Ambulance with Artificial Intelligence
NeuroSpring is helping to develop an artificial intelligence-based medical device that will diagnose patients with neurological emergencies such as stroke in the ambulance, and then direct their immediate treatment.
Where we work
External reviews

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Our results
How does this organization measure their results? It's a hard question but an important one.
Number of research studies conducted
This metric is no longer tracked.Totals By Year
Population(s) Served
Adults
Related Program
Diagnosing Neurological Emergencies in the Ambulance with Artificial Intelligence
Type of Metric
Output - describing our activities and reach
Direction of Success
Increasing
Context Notes
NeuroSpring supports medical device programs by completing research studies and engineering activities needed to support and advance their development, with the aim of enabling their clinical use.
Number of job skills training courses/workshops conducted
This metric is no longer tracked.Totals By Year
Population(s) Served
Adolescents
Related Program
Diagnosing Neurological Emergencies in the Ambulance with Artificial Intelligence
Type of Metric
Outcome - describing the effects on people or issues
Direction of Success
Increasing
Context Notes
NeuroSpring trains high school students in skills related to the various projects it supports. Intern training includes animal research skills and computer programming for medical device development.
Goals & Strategy
Learn about the organization's key goals, strategies, capabilities, and progress.
Charting impact
Four powerful questions that require reflection about what really matters - results.
What is the organization aiming to accomplish?
NeuroSpring supports research in the neurosciences with the aim of creating new medical products to treat neurological diseases. Our mission is to advance neuroscientific research and training that drives improved healthcare for the underserved.
What are the organization's key strategies for making this happen?
NeuroSpring puts charitable donations to use in the research and development new medical therapies. Organizational support comes from donations and intellectual property purchase fees.
What are the organization's capabilities for doing this?
NeuroSpring has a volunteer staff of scientists who are responsible for the daily management of its projects. NeuroSpring also has on its volunteer staff medical writers and grant experts who assist with fundraising efforts. NeuroSpring's staff also participates in several educational activities including Skype-a-Scientist presentations to primary grade classes around the country, a high school internship program, and a scholarship program for young scientists. NeuroSpring has raised funds to complete research projects supporting development of key medical device technologies. Finally, NeuroSpring has a Clinical Program Board composed of world-recognized neurologists who provide strategic guidance and quality oversight to the work conducted by the organization.
What have they accomplished so far and what's next?
Previous projects excluding the facial nerve stimulator and artificial intelligence diagnostic medical device are listed below:
The Haptoglobin - Vasospasm Project
Cerebral artery vasospasm is a constriction of brain arteries developing several days after subarachnoid hemorrhage. Vasospasm is the primary cause of morbidity and mortality in subarachnoid hemorrhage patients who survive the initial hemorrhage. Support by an American Heart Association grant, NeuroSpring's research found a protein in the blood - haptoglobin - to be the strongest risk factor for predicting the development of vasospasm in subarachnoid hemorrhage patients.
The Ouabain - Pseudotumor Project
Pseudotumor cerebri (also known as idiopathic intracranial hypertension) is a headache condition that often damages the vision. Caused by an increase in pressure inside the skull, pseudotumor was previous not known to have a cause. With support from the National Headache Foundation, NeuroSpring was first to discover a link between levels of the steroid, ouabain, and pseudotumor cerebri.
The Glucocorticoid - Traumatic Brain Injury Project
A family of steroids known as glucocorticoids has often been studied as a possible therapy for traumatic brain injury patients, but with conflicting and confusing results. NeuroSpring evaluated the literature, and its findings suggest that glucocorticoids may be effective but only in certain types of traumatic brain injury patients.
The Insula Stroke Project
Previous research has suggested that stroke in a certain part of the brain called the insula cortex are particularly dangerous because it affects cardiac function. NeuroSpring's research indicates that the association between stroke in the insula and poor outcomes is not so straightforward as previously believed.
Financials
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Operations
The people, governance practices, and partners that make the organization tick.
Connect with nonprofit leaders
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- Analyze a variety of pre-calculated financial metrics
- Access beautifully interactive analysis and comparison tools
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Connect with nonprofit leaders
SubscribeBuild relationships with key people who manage and lead nonprofit organizations with GuideStar Pro. Try a low commitment monthly plan today.
- Analyze a variety of pre-calculated financial metrics
- Access beautifully interactive analysis and comparison tools
- Compare nonprofit financials to similar organizations
Want to see how you can enhance your nonprofit research and unlock more insights? Learn More about GuideStar Pro.
NeuroSpring
Board of directorsas of 04/30/2023
Dr. Michael Coco
Ms. Tamara Heaton
Michael Coco
Coco Communications
Tamara Heaton
Wayne State University
Board leadership practices
GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.
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Board orientation and education
Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Not applicable -
CEO oversight
Has the board conducted a formal, written assessment of the chief executive within the past year ? Not applicable -
Ethics and transparency
Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes -
Board composition
Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Not applicable -
Board performance
Has the board conducted a formal, written self-assessment of its performance within the past three years? Yes
Organizational demographics
Who works and leads organizations that serve our diverse communities? Candid partnered with CHANGE Philanthropy on this demographic section.
Leadership
The organization's leader identifies as:
The organization's co-leader identifies as:
No data
Race & ethnicity
No data
Gender identity
No data
No data
Sexual orientation
No data
Disability
No data
Equity strategies
Last updated: 04/30/2023GuideStar partnered with Equity in the Center - an organization that works to shift mindsets, practices, and systems to increase racial equity - to create this section. Learn more
- We ask team members to identify racial disparities in their programs and / or portfolios.
- We analyze disaggregated data and root causes of race disparities that impact the organization's programs, portfolios, and the populations served.
- We seek individuals from various race backgrounds for board and executive director/CEO positions within our organization.