Disease, Disorders, Medical Disciplines


Funding Pediatric Brain Cancer Research

Atkinson, NE


The Team Jack Foundation raises money to fund impactful pediatric brain cancer research and works to create national awareness for the disease

Ruling Year


Founder & Board Co-Chair

Andrew Hoffman

Founder & Board Co-Chair

Brianna Hoffman

Main Address

PO Box 607 47640 E. HWY 20, Suite 2

Atkinson, NE 68713 USA


research, brain tumor research, childhood cancer





Cause Area (NTEE Code)

Fund Raising and/or Fund Distribution (G12)

IRS Filing Requirement

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Social Media


Programs + Results

What we aim to solve

Each year approximately 4,630 kids are diagnosed with brain tumors. These 4,630 kids are dealing with an abnormal growth in the most sensitive part of their body. This is the part of the body that controls speech, balance, running, jumping, talking, hearing, smelling, loving. It is a disease that is killing kids faster than any other childhood cancer. It is No. 1. While it is true that nearly 30% of all children afflicted by a brain tumor will pass from their disease, it is also true that the remaining 70% that actually survive the disease are often times left with permanent disabilities that they will spend a lifetime trying to overcome or compensate for. Team Jack is working to fund research for better, kinder treatment and to try to find a cure. Treatments are over 30 years old and this must change.

Our Sustainable Development Goals

Learn more about Sustainable Development Goals.


Our programs

What are the organization's current programs, how do they measure success, and who do the programs serve?

SOURCE: Self-reported by organization

Clinical Trials (MEK 162 & TAK 580) with Targeted Agents

Brain Tumor Program at University of Nebraska Medical Center

POWER5 Pediatric Brain Tumor Initiative

DIPG Research Project at Memorial Sloan Kettering

Phase 1 Diffuse Intrinsic Pontine Glioma (DIPG) Research Project at Lurie Children's Hospital

Where we work

Our Results

How does this organization measure their results? It's a hard question but an important one. These quantitative program results are self-reported by the organization, illustrating their committment to transparency, learning, and interest in helping the whole sector learn and grow.

SOURCE: Self-reported by organization

Number of research studies funded

Population(s) served

Children and youth (0-19 years)

Type of Metric

Context - describing the issue we work on

Direction of Success


Charting Impact

Five powerful questions that require reflection about what really matters - results.

SOURCE: Self-reported by organization

What is the organization aiming to accomplish?

What are the organization's key strategies for making this happen?

What are the organization's capabilities for doing this?

How will they know if they are making progress?

What have they accomplished so far and what's next?

Funding research that focuses on identifying brain cancer genetic mutations, and then treating those mutations with chemically engineered smart drugs, is a priority. The result will be kinder, gentler, and more successful treatment protocols. In addition to funding research to develop effective drug therapies, the Team Jack Foundation also funds neurosurgical research. A successful brain tumor resection helps set the stage in the fight against brain cancer. One of the best defenses against a brain tumor is a successful neurosurgery. Since 2013, the Team Jack Foundation has been thankful to be able to contribute to research in a variety of areas. We have committed to-date over $8 million to 8 different projects! Research aims include 5 key areas: 1) Identifying new genetic mutations that are causing brain tumors. 2) Trying to enable the drugs to get through the blood-brain barrier. 3) Clinical trials offering new treatments to kids with brain tumors. 4) Evaluating whether new brain-penetrant molecules are effective in treatment of brain tumors. 5) Helping build and support a pediatric brain tumor program in Nebraska.

Team Jack's objective is to fund research at the top research centers in the world -- fast to find a cure for child brain cancer and ensure that treatments for brain cancer are better for these children. The Team Jack Foundation's strategies are as follows:

1. Create a brain tumor program at UNMC in Nebraska. Improve the quality of brain tumor treatment in the Midwest so that children seen in the Midwest have the same treatment opportunities available to them, as children that are seen at centers of excellence. The first step for this is to hire a pediatric neuro-oncologist.

2. Fund national research programs that assist in making treatment for children less invasive and harsh.

The Team Jack Foundation has raised nearly $7,500,000 since 2013. Due to the structure of the Foundation, including a volunteer CEO, the Foundation is able to operate on low expense, therefore able to fund more research. The Foundation has a low operating budget and is able to leverage local, regional, national relationships to focus more on funding research. In addition, the Team Jack Foundation works with organizations nationally to leverage research dollars to make a bigger impact. The total disease impact is over $8.5 million.

1. The development of a brain tumor program in Nebraska that offers specialized treatment for children with brain cancer and hosts relevant clinical trials for children.
2. Continue to raise significant dollars and fund research for child brain cancer, becoming one of the top leading brain tumor Foundations in the nation.

Accomplishments: 1. Raising nearly $7.5million for research since inception. 2. Board Chair and Co-Founder named the 2016 winner of The NASCAR Foundation's Betty Jane France Humanitarian Award for his efforts in funding child brain cancer. 3. Passing of LB110. The Team Jack Foundation, in partnership Nebraska State Legislature, has committed to a $3 million project for the development of a pediatric brain tumor program at UNMC's Fred & Pamela Buffett Cancer Center. Team Jack has committed $1.5 million to this project. 4. Working with UNMC and Children's Hospital in Omaha, NE to develop a brain tumor program which includes an additional $5 million to research, pain management and education. 4. Committing to national DIPG research projects. DIPG has a 0% survival rate and the deadliest form of brain cancer. What we would like to accomplish: 1. Finding a cure for child brain cancer. 2. Finding an improved, newer, less invasive treatment option for children with brain cancer.

How We Listen

Seeking feedback from people served makes programs more responsive and effective. Here’s how this organization is listening.

Source: Self-reported by organization

the feedback loop
check_box We shared information about our current feedback practices.
How is the organization collecting feedback?
We regularly collect feedback through: electronic surveys (by email, tablet, etc.), focus groups or interviews (by phone or in person).
How is the organization using feedback?
We use feedback to: to inform the development of new programs/projects, to strengthen relationships with the people we serve.
With whom is the organization sharing feedback?
We share feedback with: our staff, our board, our funders.
What challenges does the organization face when collecting feedback?
It is difficult to: we don't have any major challenges to collecting feedback.

External Reviews




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  • Address, phone, website and contact information
  • Forms 990 for 2018, 2017 and 2016
  • A Pro report is also available for this organization.

See what's included


The people, governance practices, and partners that make the organization tick.

Need more info?

FREE: Gain immediate access to the following:

  • Address, phone, website and contact information
  • Forms 990 for 2018, 2017 and 2016
  • A Pro report is also available for this organization.

See what's included

Board Leadership Practices

GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section, which enables organizations and donors to transparently share information about essential board leadership practices.

SOURCE: Self-reported by organization


Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations?



Has the board conducted a formal, written assessment of the chief executive within the past year?



Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year?



Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership?



Has the board conducted a formal, written self-assessment of its performance within the past three years?


Organizational Demographics

Who works and leads organizations that serve our diverse communities? This organization has voluntarily shared information to answer this important question and to support sector-wide learning. GuideStar partnered on this section with CHANGE Philanthropy and Equity in the Center.

SOURCE: Self-reported; last updated 04/30/2020


The organization's leader identifies as:

Gender Identity
Male, Not Transgender (Cisgender)
Sexual Orientation
Heterosexual or Straight
Disability Status
Person without a disability

The organization's co-leader identifies as:

Race & Ethnicity
Gender Identity
Female, Not Transgender (Cisgender)
Sexual Orientation
Heterosexual or Straight
Disability Status
Person without a disability

Race & Ethnicity

No data

Gender Identity

Sexual Orientation


No data

Equity Strategies

Last updated: 04/30/2020

Policies and practices developed in partnership with Equity in the Center, a project that works to shift mindsets, practices, and systems within the social sector to increase racial equity. Learn more


We employ non-traditional ways of gathering feedback on programs and trainings, which may include interviews, roundtables, and external reviews with/by community stakeholders.

Policies and processes

We use a vetting process to identify vendors and partners that share our commitment to race equity.
We have a promotion process that anticipates and mitigates implicit and explicit biases about people of color serving in leadership positions.
We have community representation at the board level, either on the board itself or through a community advisory board.
We help senior leadership understand how to be inclusive leaders with learning approaches that emphasize reflection, iteration, and adaptability.
We engage everyone, from the board to staff levels of the organization, in race equity work and ensure that individuals understand their roles in creating culture such that one’s race identity has no influence on how they fare within the organization.