Citizens for Alternatives To Animal Research & Experimentation CAARE
Programs and results
What we aim to solve
An estimated 100 million animals are used and killed in scientific research each year, despite widespread acknowledgement that animals are inadequate models for studying human physiology and disease. The use of animal experimentation is so entrenched in scientific culture that it continues despite massive failures and exorbitant costs (the average drug takes 10 years and $1 billion to make it to market). Over 90% of drugs that pass animal tests fail in human clinical trials due to a lack of efficacy and/or safety. This high failure rate is due to the vast differences between species. Innovative technologies such as organoids, organ chips, computational modeling and more are not only humane alternatives to animal testing, they are more accurate at predicting human responses. Despite the availability of these human-relevant technologies, there is a continued over-reliance on outdated, inefficient and unethical animal research.
Our programs
What are the organization's current programs, how do they measure success, and who do the programs serve?
Research and advocacy program to reduce animal experiments
For this program CAARE is selecting specific areas of research (for example Alzheimer’s, autism, PTSD, etc.) to demonstrate that there are available, effective alternatives to using animals.
We are preparing authoritative reports that detail scientifically valid alternatives and illustrate how the use of animal experiments has failed to bring about effective cures or treatments for these areas.
The reports are then disseminated through the services of a professional public relations firm to help CAARE publish and promote these reports online and distribute to the media, policy-makers and organizations which advocate for these specific areas of medical need. (For example, The Alzheimer’s Association).
Where we work
Our results
How does this organization measure their results? It's a hard question but an important one.
Number of petition signatures
This metric is no longer tracked.Totals By Year
Type of Metric
Output - describing our activities and reach
Direction of Success
Increasing
Number of Facebook followers
This metric is no longer tracked.Totals By Year
Population(s) Served
Adults
Type of Metric
Output - describing our activities and reach
Direction of Success
Increasing
Goals & Strategy
Learn about the organization's key goals, strategies, capabilities, and progress.
Charting impact
Four powerful questions that require reflection about what really matters - results.
What is the organization aiming to accomplish?
CAARE is working to change the current paradigm of widespread, repetitive, and unnecessary animal testing, and to dispel the myth that we must use animals for medical progress.
Despite astounding technological advances that provide far superior, human-relevant data, animal research remains the default method for current research and testing. CAARE believes this is because there is a lack of awareness of other options, and a lack of government and private funding for non-animal testing.
What are the organization's key strategies for making this happen?
CAARE is working to change the overreliance of animal research by raising awareness through our website, electronic communications, and detailed scientific reports about how the abundance of new technologies can successfully replace animal research.
CAARE educates the public, media, legislators and scientists about opportunities to replace animal research with new and emerging scientific modalities not requiring the use of animals.
We raise awareness about the cruelty and inefficiency of animal methods, the superiority of human-relevant alternatives and we mobilize our followers to participate in campaigns that target research conducted on animals that is replaceable with alternatives. CAARE engages in outreach campaigns to educate about non-animal methods using e-newsletters, our website, social media, scientific reports and press releases.
CAARE promotes legislation to end the use of animals in federally funded research. We maintain a legislative specialist who speaks with Congress to advance non-animal research.
Our legislative efforts are designed to have the maximum impact, as exemplified by our proposed bill, which not only would create a center for alternatives but would require NIH to release full information on all species used, and submit a plan for reducing the use animals in research and testing.
We prepare authoritative information that details scientifically valid alternatives to using animals for medical disorders. This information is disseminated to relevant audiences, such as health care professionals, patient advocacy groups, research funders, and legislators who appropriate research money.
What are the organization's capabilities for doing this?
CAARE’s staff and advisory board have specific knowledge and extensive scientific expertise on replacing animals in experiments, as well as success with prior campaigns and initiatives to replace animals in a range of experiments. Our legislative outreach staff has over a decade of experience in major, successful federal legislative efforts for animals.
What have they accomplished so far and what's next?
CAARE campaigns successfully ended lethal brain experiments on cats at State University of New York in 2019 and in 2017 CAARE ended experiments on beagles at the University of Missouri.
CAARE has prepared an extensive report examining the use of animals to study PTSD, complete with hundreds of scientific citations, clearly demonstrating that there are effective alternatives to using animals. We will use our report to promote cutting federal funding for PTSD experiments on animals. Additionally, this marks the beginning of our Terror In The Lab campaign, in which we uncover and take action against cruel and unnecessary experiments done to animals for PTSD research.
After more than a year of dedicated congressional outreach, CAARE was instrumental in getting The Humane Research and Testing Act of 2020 (H.R. 8633) introduced in November of 2020. Sponsored by Representatives Alcee Hastings (D-FL) and Vern Buchanan (R-FL), the bill, if passed, will establish the National Center for Alternatives to Animals in Research under the National Institutes of Health (NIH) which will effectively replace animal experimentation by developing, funding and incentivizing non-animal methods of research. Importantly, it will also require the NIH to track all vertebrate animals – including rats, mice, birds and fish – used in experiments and to report progress at decreasing their use biannually.
CAARE will work to get H.R. 8633 passed through legislative and media outreach and campaigning.
Financials
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Operations
The people, governance practices, and partners that make the organization tick.
Connect with nonprofit leaders
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- Analyze a variety of pre-calculated financial metrics
- Access beautifully interactive analysis and comparison tools
- Compare nonprofit financials to similar organizations
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Connect with nonprofit leaders
SubscribeBuild relationships with key people who manage and lead nonprofit organizations with GuideStar Pro. Try a low commitment monthly plan today.
- Analyze a variety of pre-calculated financial metrics
- Access beautifully interactive analysis and comparison tools
- Compare nonprofit financials to similar organizations
Want to see how you can enhance your nonprofit research and unlock more insights? Learn More about GuideStar Pro.
Citizens for Alternatives To Animal Research & Experimentation CAARE
Board of directorsas of 04/21/2024
Barbara Stagno
CAARE
Lawrence D'Antonio
Ramapo College
Matthew Calarco
California State University Fullerton
Board leadership practices
GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.
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Board orientation and education
Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Yes -
CEO oversight
Has the board conducted a formal, written assessment of the chief executive within the past year ? No -
Ethics and transparency
Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes -
Board composition
Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Yes -
Board performance
Has the board conducted a formal, written self-assessment of its performance within the past three years? No
Organizational demographics
Who works and leads organizations that serve our diverse communities? Candid partnered with CHANGE Philanthropy on this demographic section.
Leadership
The organization's leader identifies as:
Race & ethnicity
No data
Gender identity
No data
Transgender Identity
No data
Sexual orientation
No data
Disability
No data
Equity strategies
Last updated: 11/14/2020GuideStar partnered with Equity in the Center - an organization that works to shift mindsets, practices, and systems to increase racial equity - to create this section. Learn more
- We engage everyone, from the board to staff levels of the organization, in race equity work and ensure that individuals understand their roles in creating culture such that one’s race identity has no influence on how they fare within the organization.