The Human Immunome Project

The Human Immunome Project is an independent global non-profit organization dedicated to developing AI based models the immune system to rethink research across diseases, and ultimately extend and enhance the healthy lifespan of 8 billion human beings.

The Human Immunome Project is compiling the biggest dataset of biomedicine at a population scale. We will use this data to create the first AI model of the human immune system, which will help us speed up the testing process and make the development of vaccines and treatments faster, cheaper and more effective.

The goal is to collect detailed information on the complex network of genes, proteins, cells, and molecules that constitute the human immunome, and to do this for diverse, global populations over time. Then, by harnessing the power of AI, scientists can crunch these data to generate models of the human immune system. These models can then be used to develop new vaccines and treatments where there none, to protect our populations must vulnerable to disease, and accelerate research across infectious and non-communicable diseases.

In the work that it does, and how it does that work, HIP is committed to diversity, equity and inclusion in all facets of our organization and work and believe it is essential to our achieving our goals. Our DEI commitment and effort encompasses:

• Create AI models that reflect human immunological diversity
- scientific priorities and ethical inclusion in research
• advisory and Board committees
• conferences hosted by HVPI
• selection of vendors and consultants that HVPI engages
• workplace hiring of staff and fellows.

Our commitment is essential to our global mission and vision of a world where every person has a chance to enjoy a longer and healthier life.

HIP works with the top researchers and scientific institutions across the world to carry out its mission. Through our global consortium we enable leading researchers and scientists around the world to work together in designing, implementing, and analyzing outputs from scientific studies. We also partner with leading academic institutions to study specific aspects of immunity and ensure comprehensive data analytics and management.

We have open-sourced the first sequencing of the human immune system, used machine learning to predict who will and will not respond to vaccination, and established one of the world's leading scientific consortia and immunology-based research networks. Our network has published seminal studies on the human immunome in high-profile journals, and we’ve made our data publicly available for additional research. HIP has also become a highly impactful advocacy organization, helping to catalyze new ways of working and thinking for human immunology, one of the great frontiers of biomedicine.

In 2022, the Human Immunome Project held a Summit and is now working to develop and implement a strategic plan for creating AI models of the human immunome. The strategic planning process will include follow-on summits held in Europe, Asia, and Africa. At these meetings, participants will delve deeper into some of the key questions related to this initiative, including defining the grand scientific challenges that could be accomplished in the next five years.

Over the next several years, HIP will embark on launching a series of Grand Challenges to solve core problems in human immunology, and lay the foundation for increasingly powerful models of the human immunome.