Diabetes Research Institute Foundation, Inc.

The Time for a Cure is Now

aka DRIF   |   Hollywood, FL   |  http://www.diabetesresearch.org

Mission

The Mission of the Diabetes Research Institute Foundation is to provide the Diabetes Research Institute with funding necessary to cure diabetes now.

Ruling year info

1973

CEO

Sean Kramer

Main address

200 South Park Road Suite 100

Hollywood, FL 33021 USA

Show more contact info

EIN

59-1361955

NTEE code info

Research Institutes and/or Public Policy Analysis (G05)

Specifically Named Diseases Research (H80)

IRS filing requirement

This organization is required to file an IRS Form 990 or 990-EZ.

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Communication

Programs and results

What we aim to solve

SOURCE: Self-reported by organization

At the Diabetes Research Institute Foundation, the goal is to cure diabetes, a chronic, life-threatening disease that affects more than 29 million people in the United States, and hundreds of millions more worldwide - at a rate that is rising to epidemic proportions. The discovery of a cure would mean restoring natural insulin production and normalizing blood glucose levels without imposing risks to patients living with this disease.

Our programs

SOURCE: Self-reported by organization

What are the organization's current programs, how do they measure success, and who do the programs serve?

Research to Cure Diabetes

At the Diabetes Research Institute (DRI), the vision is to achieve a biological cure for diabetes by restoring natural insulin production and normalizing blood sugar levels without imposing other risks. Since its inception, the DRI has made significant contributions to the field of diabetes, pioneering many of the techniques used in diabetes centers around the world. Having already shown that diabetes can be reversed through islet transplantation, the DRI is building upon their groundbreaking discovery by focusing on three critical areas of research simultaneously: (1) engineering a site within the body to house transplanted insulin-producing (islet) cells, (2) sustaining the survival of these cells without the use of harsh immunosuppressive drugs, and (3) creating an unlimited supply of islets to treat the millions living with diabetes.

Population(s) Served
Adults
People with diseases and illnesses
Children and youth
People with disabilities

The Diabetes Research Institute Foundation provides important diabetes information and research updates to the public through many different outlets. Our various publications, including the annual report and newsletter, are distributed by mail, as well as housed and archived on our website at DiabetesResearch.org. The website is also a reference for those looking to learn more about the work of the DRI.

Current news and updates are shared with the public through our many social media channels, including Facebook, Twitter, YouTube, LinkedIn and Pinterest, among others.

The DRI Foundation also hosts a variety of research updates presented by DRI researchers throughout the year to inform constituents about the progress being made toward a cure for diabetes.

Population(s) Served

Where we work

Our results

SOURCE: Self-reported by organization

How does this organization measure their results? It's a hard question but an important one.

Number of research studies conducted

This metric is no longer tracked.
Totals By Year
Population(s) Served

Adults, Children and youth, People with diseases and illnesses, Researchers

Related Program

Research to Cure Diabetes

Type of Metric

Output - describing our activities and reach

Direction of Success

Increasing

Goals & Strategy

SOURCE: Self-reported by organization

Learn about the organization's key goals, strategies, capabilities, and progress.

Charting impact

Four powerful questions that require reflection about what really matters - results.


The Diabetes Research Institute (DRI) was created for one reason – to cure diabetes – which is and will continue to be its singular focus until our goal is realized. Diabetes Research Institute (DRI) scientists have already shown that transplanting insulin-producing islet cells can restore natural insulin production, eliminate the need for shots, restore normal blood sugar levels and free patients from frightening hypoglycemic episodes. Some patients in clinical trials have been insulin-free for more than a decade. Islet transplantation is the only procedure outside of a full organ (pancreas) transplant that has been able to free patients from insulin injections. Currently, islet transplantation is an experimental procedure, limited to only the most severe cases of type 1 diabetes. One of the main reasons is that patients must take powerful drugs to prevent rejection of the donor cells. Another reason is that are simply not enough donor cells available to treat everyone who can benefit. DRI researchers are working diligently to build upon this progress and address these remaining challenges.

Diabetes Research Institute scientists are targeting three critical areas of research simultaneously: (1) engineering a site within the body to house transplanted insulin-producing (islet) cells, (2) sustaining the survival of these cells without the use of harsh immunosuppressive drugs, and (3) creating an unlimited supply of islets to treat the millions living with diabetes.

The DRI is a world leader in cure focused research and is the largest and most comprehensive research center dedicated to curing diabetes. A designated Center of Excellence at the University of Miami Miller School of Medicine, the DRI has made significant contributions to the field of diabetes, pioneering many of the techniques used in diabetes centers worldwide. Few research centers have the ability to translate promising ideas from the lab to the patient. The DRI leverages this ability by housing all phases of research under one roof – translating discoveries from basic research (in the lab), to pre-clinical research (in large animal models), and finally to clinical research (in patients). A unique aspect of the DRI is its core philosophy of collaboration. The Diabetes Research Institute serves as the hub of the DRI Federation, a worldwide alliance of researchers that share knowledge, overcome barriers and accelerate progress. Working closely with these scientific colleagues, researchers at the DRI in Miami investigate more strategies, share more ideas, and accomplish more, bringing promising findings to patients more quickly than ever before. These collaborations also allow philanthropic dollars to go further. Research can be conducted at partner centers in countries with a lower cost basis. We believe that the fastest and most efficient way to end diabetes is to work together toward a cure. The DRI has developed a strategic roadmap for reaching a biological cure for diabetes. First, we've assembled a team of researchers with expertise in the scientific disciplines necessary for attacking diabetes, like bio- and tissue engineers, immunologists, stem cell researchers, molecular biologists, surgeons, clinicians and more. Second, only the most promising research discoveries that can benefit patients advance to further stages of testing so no time or money is wasted. The DRI has become the world leader it is today with the substantial funding provided by the Diabetes Research Institute Foundation. The organization, which began in 1971 with a group of parents who were dedicated to finding a cure for their children who had diabetes, has grown into a coalition of business leaders, celebrities, scientists, clinicians and families is focused on providing the necessary funding to cure diabetes now. The seed funding provided by the DRI Foundation enables DRI scientists to jump-start new research projects and pursue innovative findings. This support fills the gap until grant money is awarded from external funding sources allowing progress to continue without delay - because tomorrow is not soon enough to find a cure.

The DRI's goal is to restore natural insulin function in people living with diabetes. The DRI and its collaborators have shown that transplanting insulin producing islet cells makes this possible. Patients participating in clinical islet transplant trials have lived insulin free for more than ten years. The main challenges that must be overcome are: 1) Site: Developing an optimal environment to house and protect the islet cells which mimics the native pancreas; 2) Sustainability: Retraining the immune system to prevent the rejection of transplanted cells without the need for systemic anti-rejection drugs, and reversing the autoimmune attack which is responsible for the onset of type 1 diabetes; 3) Supply: Identifying, developing and/or regenerating an unlimited supply of cells to sense blood glucose levels and produce insulin. Many projects are underway to address these three overarching issues. An FDA-approved clinical trial is now underway to test a new transplant Site in the body. Since medical research involves developing an understanding of previously uncharted territory, DRI scientists are continually expanding and reshaping their work as promising new theories emerge and data is gathered. Successful research outcomes are published in leading peer reviewed scientific journals that substantiate our progress and share it with the scientific community.

Financials

Diabetes Research Institute Foundation, Inc.
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Operations

The people, governance practices, and partners that make the organization tick.

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Diabetes Research Institute Foundation, Inc.

Board of directors
as of 9/9/2021
SOURCE: Self-reported by organization
Board chair

Mr. William Fishlinger

Gramercy Risk Holdings, LLC

Term: 2016 - 2021

Marlene Berg

No Affiliation

Ronald Darling, Jr.

TBS, SNY, and WPIX

Piero Gandini

Flos Lighting

Esther Goodman

Conyers Consulting Group LLC

Marc Goodman

Conyers Consulting Group LLC

Bonnie Inserra

Inserra Family Foundation

Eleanor Kosow

No Affiliation

Sandra Levy

No Affiliation

Ramon Poo

Altira, Inc.

Charles Rizzo

The Rizzo Group

Ricardo Salmon

Hillview Capital Advisors

Jill Viner

No Affiliation

Bruce Waller

Gold Coast Properties and Development, Ltd.

John Doscas

Axios Capital Management LLC

Sean McGarvey

North America's Building Trades Unions

David Sherr

One William Street Capital

Marc Goldfarb

Full Beauty Brands

Bruce Siegel

First Long Island Investors

Harold Doran, Jr.

No Affiliation

Lindsey Inserra-Hughes

Inserra Supermarkets

Rizzo Stephen

RizzoGroup

Board leadership practices

SOURCE: Self-reported by organization

GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.

  • Board orientation and education
    Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Yes
  • CEO oversight
    Has the board conducted a formal, written assessment of the chief executive within the past year ? Yes
  • Ethics and transparency
    Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes
  • Board composition
    Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Yes
  • Board performance
    Has the board conducted a formal, written self-assessment of its performance within the past three years? Yes

Organizational demographics

SOURCE: Self-reported; last updated 9/3/2021,

Who works and leads organizations that serve our diverse communities? GuideStar partnered on this section with CHANGE Philanthropy and Equity in the Center.

Leadership

The organization's leader identifies as:

Race & ethnicity
Hispanic/Latino/Latina/Latinx
Gender identity
Male, Not transgender (cisgender)
Sexual orientation
Heterosexual or Straight
Disability status
Person without a disability

Race & ethnicity

Gender identity

 

Sexual orientation

No data

Disability