Medical Research

One Mind

Healthy Brains for All

aka One Mind   |   Rutherford, CA   |  https://www.onemind.org

Mission

One Mind's mission is to radically accelerate cures for brain illnesses and injuries by funding and fostering scientific collaborations and initiatives.

Ruling year info

2009

Board President, Co-Founder

Garen Staglin

Co-Founder

Mrs. Shari Staglin

Main address

P.O. Box 680

Rutherford, CA 94573 USA

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Formerly known as

Staglin Music Festival for Mental Health

International Mental Health Research Organization

IMHRO

Rutherford Charitable Organization

EIN

68-0359707

Cause area (NTEE code) info

Brain Disorders (H48)

Brain Disorders (G48)

IRS filing requirement

This organization is required to file an IRS Form 990 or 990-EZ.

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Communication

Programs and results

What we aim to solve

SOURCE: Self-reported by organization

Untreated brain illness or injury is a life-altering condition that significantly debilitates individuals, their friends and families, and the surrounding economy. The global economic burden from mental illness alone is estimated at nearly $2.5 trillion per year, projected to rise to $6 trillion by 2030. In addition, there are hurdles within the current research landscape that slow the pace of biomedical brain research. Recent estimates indicate that it takes an average of 17 years for medical discoveries to be applied in community settings – the place where they can help patients who struggle. This delay is unacceptable and must be accelerated. Overcoming these limitations is what drives One Mind's efforts. With a focus on fostering paradigm-shifting scientific research and collaborations, our work is changing the culture within the current research landscape to radically accelerate cures for brain illnesses and injuries now.

Our programs

SOURCE: Self-reported by organization

What are the organization's current programs, how do they measure success, and who do the programs serve?

AURORA

The AURORA study is a major national research initiative that is working to improve the understanding, prevention, and recovery of individuals who have experienced a traumatic event. Knowing that the outcomes of this study could fundamentally change the paradigm of care for those who suffer from post-traumatic stress related disorders, and wanting to accelerate the outcomes of the AURORA study, in 2017 One Mind set forth the goal of raising an additional $7.9 million in donor-generated funds over a 5-year period to be given to the study (As of June 2018, One Mind has given $1 million to AURORA).

Population(s) Served
People with psychosocial disabilities

Serious Psychiatric Illness (SPI) is a major public health issue, devastating individuals, families and society. Starting between ages 16 and 30, the one in 25 people who live with SPI face hallucinations and delusions (psychosis), lack of motivation, inability to think clearly, tremendous social stigma, and high rates of substance abuse and homelessness, leading often to suicide. Schizophrenia alone costs the U.S. $156 billion annually. Currently only 8% of youth with early SPI receive gold-standard early treatment, and only 22% of patients fully recover from SPI. Through our ASPIRe (Applications for Serious Psychiatric Illness Recovery) program, we aim to enable 75% of youth with early SPI to receive quality evaluations and treatment and the proportion of patients who recover from SPI to rise to 75% by 2040. In the near term, our immediate interest consists of two deliverables: (1) To start a learning healthcare network in California for early SPI community-based programs to share data and ideas so that each can learn from one another’s strengths, improving patient care on a large scale. (2) To pilot research-based care innovations and support innovative ways to enroll young people with early SPI.

Population(s) Served
People with psychosocial disabilities
Adolescents (13-19 years)

Supported by One Mind, and partnering with 18 Level 1 trauma center enrollment sites across America, the TRACK-TBI study is collecting detailed clinical data of 3,000 TBI injured patients, following the progression of their injuries for a year. The biomarkers being developed via the TRACK-TBI and TED studies will enable stratification of the concussion population and define concussion sub-types, thereby enabling researchers to more effectively match patients to clinical trials and in the end, provide precise targets for the development of new therapies and devices to treat TBI.

Population(s) Served
Adults
Adolescents (13-19 years)
Budget
$150,000

PsyberGuide (psyberguide.org) is a website, managed by One Mind, that rates and reviews software for treating mental health conditions. Because the FDA is not regulating this space, PsyberGuide aims to step in to help consumers make sense of the landscape and choose what software might help them best. It provides objective ratings by a specially selected team of scientists, and offers a consumer rating system so that real users can share their own impressions of specific programs. Today, the PsyberGuide team has rated 80 popular programs for a range of conditions, including schizophrenia, mood disorders, anxiety, and post-traumatic stress.

Population(s) Served
Young Adults (20-25 years)
Budget
$233,500

Given the challenges of understanding and finding therapies for brain illnesses and injuries, the One Mind Rising Star Awards encourage the community of researchers to innovate in basic and translational science to benefit patients, while supporting the research of emerging leaders in the field. The overarching goal is to award promising, early career investigators an opportunity to enhance or accelerate research on major neuropsychiatric disorders, such as anxiety, addiction, bipolar disorder, depression, post-traumatic stress, schizophrenia, and traumatic brain injury. Total funding for each of the three Rising Star Awards is $250,000, with $83,333 distributed annually over a 3-year period.

Population(s) Served
Adults
Adolescents (13-19 years)
Budget
$250,000

Where we work

Our results

SOURCE: Self-reported by organization

How does this organization measure their results? It's a hard question but an important one.

Number of brain researchers funded

This metric is no longer tracked.
Totals By Year
Related Program

Rising Star Research Awards

Type of Metric

Output - describing our activities and reach

Direction of Success

Increasing

Context Notes

Through our annually held Rising Star Awards grant program, One Mind funds some of the best and brightest early-career brain researchers, giving them each a $250,000 grant.

Charting impact

SOURCE: Self-reported by organization

Five powerful questions that require reflection about what really matters - results.

What is the organization aiming to accomplish?

One Mind's near-term goal is to improve life prospects for youth throughout our society by establishing prevention/early intervention as an easily accessible, insurance-reimbursed means to address the growing prevalence of serious behavioral illness. One Mind's middle-term goal is to enable the development of safer, more effective treatments, both remedial and preventive, for all severe psychiatric diseases. One Mind's long-term goal is to enable the neuroscientific discovery and development of cures for all brain diseases, as quickly as possible. We also seek to raise awareness and educate people to understand the nature of brain disease and reduce the discrimination and stigma that is often associated with people who have a brain disorder.

To accomplish nationwide psychosis prevention/early intervention (PEI) in the near term, we have funded the North American Prodrome Longitudinal Study (NAPLS) consortium to develop effective tools to detect and treat psychosis as early as possible. We are collaborating with this consortium, the federal government, our partner nonprofit, One Mind, and the Steinberg Insititute to establish a standardized, pooled knowledge network which can link existing and new PEI clinics to improve patient outcomes. University PEI clinics will assist community clinics in collecting and sharing research data to validate innovative treatments. Once an evidence base is established that PEI works, insurance providers can be persuaded to provide coverage so that youth nationwide can benefit from preventive care.<br/>To accomplish the development of better psychiatric treatments, we are funding the most promising translational projects of "Rising Star" neuroscientists, to make better interventions available within several years, and to launch productive careers.<br/>To accomplish brain disease cures as soon as possible, we fund basic brain research to better understand the nature of psychiatric diseases. We work with our partner One Mind to enable Open Science principles (large-scale standardized data sharing and research collaboration). Through relationship-building and tools to enable scientists to pool their data and their talents, we believe cure research can be radically accelerated.<br/>To raise awareness we regularly post information on latest developments in brain research and advocacy on our social media channels and website. We host dinners across the country to engage potential supporters and provide information.

Our relationships throughout the brain health community, including in advocacy, industry, research and government, enable us to raise funds, direct research and form public/private partnerships toward the fulfillment of all three of our main goals.<br/>Our Board members have considerable experience in public and private/non - profit Board governance They each have a friend or family member with a brain disease and are highly motivated for One Mind Institute to achieve its mission and goals.

We will measure progress toward standardized prevention/early intervention for psychosis in the number of centers that join or arise within our PEI knowledge network, the population they reach and the proportion of clients that do not convert to psychosis during engagement.<br/>We measure progress toward better treatments in the number of molecular targets discovered, the number of potential new treatments in development, the number of new treatments validated, and the number made available.<br/>So far, we measure progress toward cures in the number of promising new approaches our funded scientists devise and investigate.<br/>We track our communication and awareness raising by the number of followers and level of engagement on social media as well as on our website.

Currently, the NAPLS psychosis prevention network includes 9 main research/treatment centers and several satellite clinics. Together with the RAISE early intervention centers and community clinics funded by SAMHSA and State funding, there are about over 200 such clinics known nationwide. Our principals aim to achieve government and private funding to open hundreds more over the next ten years. So far, the NAPLS has treated 720 at-risk clients, 60% of which did not convert to psychosis during their 2 year treatment. We hope to increase that proportion to 90% within 20 years. In these clinics and the community clinics that have arisen more recently, PEI treatment has cut hospitalization rates by 50% among those treated. We hope to reduce rates by 75% within ten years.<br/>Toward better interventions for severe psychiatric disease, since 1996 we have funded the discovery of 21 biological targets for the development of new treatments, the testing of 19 such treatments, the validation of 3 such treatments, and the availability, to clinical research subjects, of 3 such treatments. We hope to enable at least 10 new treatments in testing to be generally clinically available within 20 years.<br/>Toward cures, we have funded the investigation of 28 radically innovative approaches to treating psychiatric disease. Of these, we believe that 3 in particular (prevention, app-based cognitive training, and re-syncing brain circuits through neuro-electrical stimulation) offer dramatic potential to improve lives.<br/>We have more than 8,200 fans on our Facebook site, our mailing list includes more than 7,000 subscribers and our website has hundreds of unique visitors daily.

Financials

One Mind
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Operations

The people, governance practices, and partners that make the organization tick.

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Connect with nonprofit leaders

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One Mind

Board of directors
as of 11/26/2019
SOURCE: Self-reported by organization
Board chair

Garen Staglin

One Mind Co-Founder

Vince Rinaldi

Founder and CEO of Corporate Advisors Inc.; Former President of PNC Equipment Finance Division; Ronald McDonald House Board Member; Lindner Center of Hope Board Member

Shari Staglin

Co-Founder of One Mind; Co-Owner and CEO of Staglin Family Vineyard; Founding President and Board Member of Staglin Music Festival for Brain Health; NARSAD Director Emeritus

Gwill York

Lighthouse Capital Partners Co-Founder; Comdisco Ventures Former Vice President; Museum of Science Board of Trustees; Systems Biology Department of Harvard Medical School Advisory Council

Marlys Palumbo

Van Ness Feldman; All Star Orchestra President of the Board of Directors, President; Seattle Symphony Orchestra Honorary Lifetime Trustee

Patrick Kennedy

Co-Founder of One Mind; Former U.S. Congressman of Rhode Island; Next Chapter LLC

Gary Bridge

Retired Managing Director of Horsley Bridge Partners; Accordia Global Health Foundation International Council Member

Gary Gottlieb

President and CEO of Partners HealthCare Systems; Professor of Psychiatry, Harvard Medical School

Caryl Athanasiu

Wells Fargo & Company, Executive Vice President and Chief Operational Risk Officer

Nancy Dearman

Vice Chairman of Kotter International

Garen Staglin

Co-Founder of One Mind; Co-Owner of the Staglin Family Vineyard; Partner, private equity firms; Former NARSAD Board Member

Board leadership practices

SOURCE: Self-reported by organization

GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.

  • Board orientation and education
    Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Yes
  • CEO oversight
    Has the board conducted a formal, written assessment of the chief executive within the past year ? Yes
  • Ethics and transparency
    Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes
  • Board composition
    Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Yes
  • Board performance
    Has the board conducted a formal, written self-assessment of its performance within the past three years? Yes

Keywords

brain health, mental illness, mental health, research, schizophrenia, depression, bipolar disorder, neuroscience, international