Augies Quest To Cure ALS Inc

We know ALS is a disease we can tackle, a problem we can solve. Because ALS is curable; it’s just underfunded. There are many needs in the ALS community, so we are singularly focused on funding translational research.

Our goal is to fund translational research that will most efficiently and effectively result in treatments for ALS. In order to do this, we will fund grants to research organizations. Our grants are milestone driven and require the research institution to spend the money directly on research (versus bricks and mortar, marketing, or overhead).

Augie’s Quest to Cure ALS raises the funds and awareness urgently needed to advance cutting-edge research, fast-track effective treatments, and ultimately, find a cure for ALS. This is done through funding the best research with the highest probability of helping families currently living with the disease.

In order to fund the right research, we must raise the money needed. Our strong Board of Directors, Leadership and Fitness Advisory Council's work with our team to create fundraising platforms that make it easy and impactful for individuals to donate to the Quest. We coordinate best in class fundraising cause campaigns, successful Gala's, and in-club fitness activations to raise money to fuel the cure.

These dollars are granted to credible research organizations that meet designated milestones with peer-review papers.

Augie's Quest to Cure ALS has experience raising the funds necessary to fund the best ALS research. Prior to becoming our own 501c3 in 2018, we'd raised almost $150 million for ALS research. Our leadership is experienced in this, and the numbers show the efficiency and ability to make it happen.

The Augie’s Quest Translational Research Center at ALS TDI honors the work, innovation and steadfast support of Augie’s Quest and its many generous and committed donors to finding a cure for ALS. Housed within ALS TDI’s Cambridge, Mass., laboratory, the Augie’s Quest Translational Research Center will help to strengthen its existing and future research efforts by aiming to dissect mechanisms of clinical ALS and use the knowledge to develop new, more powerful drug discovery platforms and facilitate more effective drug development in ALS.

• December 2021: Augie’s Quest to Cure ALS announced a $5.8 million commitment to fund the discovery of new candidate drugs to slow, stop, or even reverse ALS disease progression at the Augie’s Quest Translational Research Center through 2024. These funds will cover science staff compensation, yearly equipment costs, and additional needs at the Augie’s Quest Translational Research Center, a key component of the ALS TDI Drug Discovery Engine.

• August 2021: Augie’s Quest to Cure ALS provided $125,000 to the ALS Therapy Development Institute in honor of Phil Green so scientists at the Augie’s Quest Translational Research Center can develop the next generation human induced pluripotent stem cell models to discover key biological features that distinguish subtypes of ALS with the goal of making each of those subtypes treatable.

o January 2020: the ALS Therapy Development Institute announced the creating of the Augie’s Quest Translational Research Center at ALS TDI. This Research Center honors the work, innovation and steadfast support of Augie’s Quest and its many generous and committed donors to finding a cure for ALS. Housed within ALS TDI’s laboratory, the Augie’s Quest Translational Research Center will help to strengthen its existing and future research efforts by aiming to dissect mechanisms of clinical ALS and use the knowledge to develop new, more powerful drug discovery platforms and facilitate more effective drug development in ALS.

2. Discovery Biology Suite at ALS TDI dedicated in honor of Elizabeth Scott Bodine - changing outcomes for people living with ALS

• December 2021 $1.5 million was granted to ALS TDI in 2021 for the discovery of new drug targets, or intervention points, for the effective treatment of ALS. The discovery of a new drug target for ALS is akin to opening an entirely new avenue for slowing, stopping, or reversing a disease that has, up to now, been largely untreatable. Target discovery is the creative science that is foundational to breakthroughs in drug discovery and development and changing outcomes for people diagnosed with ALS in the future.