Advancing Ctnnb1 Cures and Treatments Inc
CTNNB1 Connect and Cure
Mission
RESEARCHING CURES AND TREATMENTS FOR CTNNB1
Ruling year
2019
President
Lauren Cochran
Main address
8 Loantaka Ln N
Morristown, NJ 07960 USA
EIN
83-4541448
NTEE code
Specifically Named Diseases (G80)
IRS filing requirement
This organization is required to file an IRS Form 990 or 990-EZ.
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Communication
Programs and results
What we aim to solve
Our programs
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Small Molecule Investigation
Research is being conducted at the Michele Jacob Lab at Tufts University. Our chief investigator is Michele H. Jacob, Ph.D along with her lab's postdoctoral scholar, Jon Alexander.
To date, the lab has completed testing of three different small molecules as corrective treatments in the mouse model of CTNNB1 syndrome. One drug has been identified as the front runner and corrects the molecular change which likely underlies remedy of the phenotypes.
Mouse work is completed and we are currently waiting for the arrival of six patient-derived IPSC cell lines to further show proof of concept.
Where we work
External reviews
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Operations
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Advancing Ctnnb1 Cures and Treatments Inc
Board of directorsas of 03/11/2023
Lauren Cochran
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