CANCER RESEARCH AND BIOSTATISTICS

We remain focused on our mission by combining our oncology experience, expertise, and innovation in oncology clinical trial management to advance treatments and help conquer cancer.

As such, our goal is to deliver for our collaborators, key partners and clients: Trusted, high quality expertise, on time and on budget.

Key Partnerships: CRAB is the Data Center for the SWOG Statistical Center. Not only is SWOG by far our largest customer, it is through that relationship that our products, services and expertise have been honed.

CRAB has long standing partnerships with other research consortia which have provided opportunities to expand our expertise beyond clinical trials. We have refined and improved cancer staging for myeloma and lung cancer through our relationship with International Myeloma Foundation and International Association for the Study of Lung Cancer, respectively. Our ongoing work with the Myeloma Institute is rich with some of the earliest use of genomic analyses in the clinical trial arena, producing prognostic and predictive markers that continue to be refined for clinical use. Similarly, as the statistical center for the Pancreatic Cancer Research Team we are working with collaborators to combine translational data to improve clinical outcomes.

CRAB's Clinical Research Services (CRS) division looks to expand the number of key partnerships we have in place with research consortia as well as pharmaceutical clients. As we continue to build and leverage our oncology expertise, we believe our client-centric approach will help us to strengthen and expand our key research partnerships.

CRAB's CEO, Antje Hoering, is collaborating with a select number of executives to address significant, and often very similar, challenges related to the generation of grant revenue, research and development, collaborating with industry, and other institutional administrative matters. The Pacific Northwest Life Sciences Executive Forum was created to bring together executive level professionals from non-profit life sciences organizations in the Pacific Northwest to mutually discuss these shared challenges, share best practices, and determine areas for potential inter-institutional or regional collaboration.

Biostatistical Services. The design and analysis of a wide variety of oncology clinical trials constitutes the majority of our work. Trials range from Phase I single or multi -institution industry sponsored to Phase III multi-institutional cooperative group trials.

Clinical Trial Services. CRAB provides an efficient and seamless suite of clinical trial services from inception of the study to publication of the results. Our statisticians design studies such that the key questions can be answered unambiguously. They work with Data Monitors and Applications Developers to create an Electronic Data Capture system that will capture data necessary for the trial. Project managers oversee the entire process to assure the study is on time and on budget. Once the study is activated our Data Managers use this powerful EDC system to perform centralized monitoring of the data in real time, assuring the data are clean, complete and accurate through resolution of queries. Our approach to centralized data monitoring reduces the need for on-site clinical monitoring except in trials requiring FDA approval. Statisticians provide interim analyses, DSM reporting and support, final analyses and writing for publication.

Training. An important part of our service delivery is the training of professionals to confidently use our systems or understand our science.

CRAB has long enjoyed a successful partnership with SWOG and other key partnerships in clinical trial work, and looks forward to great collaborations in 2017.

For more information about CRAB, please see News and Events at the following link.
http://www.crab.org/NewsEvents.aspx