Vista, CA   |
GuideStar Charity Check


EIN: 26-4207421


Reducing maternal and infant mortality attributed to amniotic fluid embolism while helping those impacted navigate paths forward.

Ruling year info


Executive Director

Mrs. Miranda Klassen

Main address

1611 S Melrose Drive Suite A #152

Vista, CA 92081 USA

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Subject area info

Diseases and conditions

Population served info

Women and girls

NTEE code info

Specifically Named Diseases (G80)

IRS subsection

501(c)(3) Public Charity

IRS filing requirement

This organization is required to file an IRS Form 990 or 990-EZ.

Tax forms


Programs and results

What we aim to solve

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Our programs

SOURCE: Self-reported by organization

What are the organization's current programs, how do they measure success, and who do the programs serve?

Amniotic Fluid Embolism Registry at Baylor College of Medicine

One of the primary goals of the AFE Foundation is to spur clinical research on amniotic fluid embolism (AFE).

The AFE Foundation has joined into a formal collaboration with Baylor College of Medicine in Houston, Texas, Wayne State University in Detroit Michigan, and the Perinatology Research Branch of the National Institute of Health (NIH) to form an international registry and biorepository of cases of amniotic fluid embolism. This registry allows for greater visibility into incidence rates, survival rates, and commonalities amongst those affected.

Population(s) Served
Women and girls

Where we work


Top Non Profit 2020

Great NonProfits

Affiliations & memberships

National Organization of Rare Disorders (NORD) 2018

MoMMA's Voices 2018

Our Sustainable Development Goals

SOURCE: Self-reported by organization

Learn more about Sustainable Development Goals.

Goals & Strategy

SOURCE: Self-reported by organization

Learn about the organization's key goals, strategies, capabilities, and progress.

Charting impact

Four powerful questions that require reflection about what really matters - results.

The AFE foundation exists to better understand AFE and identify it’s cause so that clinicians will be able to predict, prevent, and thereby reduce lives lost and collateral harm done to mothers, babies, families and communities.

Our strategy is to advance research, promote education, elevate awareness, and provide support for those impacted. We are frequently asked to speak, participate as a panelist, and lecture on amniotic fluid embolism and patient advocacy.

We are an international network of those affected by AFE, advised by a world-renowned medical advisory board comprising respected physicians, nurses, and expert researchers. The AFE Foundation also collaborates with other non-profit organizations, governmental agencies, prestigious academic institutions, and corporate partners to help carry out our mission and vision.

We have an expert community willing to participate in research and education. The Executive Director of the AFE Foundation serves on boards of various maternal health organizations. She is the Patient Advocate for the Council for Patient Safety in Women’s Health Care based in Washington D.C., Executive Committee Member for the California Maternal Quality Care Collaborative (CMQCC), Pregnancy Associated Maternal Mortality Review Committee (PAMR) Executive Advisory Member for the Institute for Perinatal Quality Improvement, and as a member of the expert panel for the Obstetric Life Support Pregnancy Resuscitation Program at Baylor College of Medicine. We are seen as the experts of AFE and revered as the primary resource for information as it pertains to AFE.

We have accomplished a great deal since 2008. Our research registry has garnered an international following and collaboration. We have published more than a dozen papers on AFE treatment and management, diagnostic criteria, subsequent pregnancies, risk factors, and how to support patients, family, and staff after a severe maternal event.

We have provided direct education to over 10,000 clinicians across the globe through lectures and panels at Grand Rounds, webinars, and medical society meetings.

More than 1,500 families are engaged in our organization and participate in various support groups, peer outreach programs, and advocacy training opportunities.

Our impact would not be possible without the generosity and engagement of our supporters. While we have much to be proud of, we know there is still a great deal of work to be done. AFE remains unpreventable and poorly understood. Mothers and their babies are still dying. We envision a world free from the devastation of AFE when all moms can experience motherhood.

How we listen

SOURCE: Self-reported by organization

Seeking feedback from people served makes programs more responsive and effective. Here’s how this organization is listening.

done We demonstrated a willingness to learn more by reviewing resources about feedback practice.
done We shared information about our current feedback practices.
  • How is your organization using feedback from the people you serve?

    To identify bright spots and enhance positive service experiences, To inform the development of new programs/projects, To identify where we are less inclusive or equitable across demographic groups, To strengthen relationships with the people we serve

  • Which of the following feedback practices does your organization routinely carry out?

  • What challenges does the organization face when collecting feedback?

    It is difficult to find the ongoing funding to support feedback collection


Fiscal year: Jan 01 - Dec 31

Revenue vs. expenses:  breakdown

SOURCE: IRS Form 990 info
Note: When component data are not available, the graph displays the total Revenue and/or Expense values.

Liquidity in 2022 info

SOURCE: IRS Form 990


Average of 45.05 over 9 years

Months of cash in 2022 info

SOURCE: IRS Form 990


Average of 31 over 9 years

Fringe rate in 2022 info

SOURCE: IRS Form 990


Average of 5% over 9 years

Funding sources info

Source: IRS Form 990

Assets & liabilities info

Source: IRS Form 990

Financial data

SOURCE: IRS Form 990


Revenue & expenses

Fiscal Year: Jan 01 - Dec 31

SOURCE: IRS Form 990 info

Fiscal year ending: cloud_download Download Data


Balance sheet

Fiscal Year: Jan 01 - Dec 31

SOURCE: IRS Form 990 info

The balance sheet gives a snapshot of the financial health of an organization at a particular point in time. An organization's total assets should generally exceed its total liabilities, or it cannot survive long, but the types of assets and liabilities must also be considered. For instance, an organization's current assets (cash, receivables, securities, etc.) should be sufficient to cover its current liabilities (payables, deferred revenue, current year loan, and note payments). Otherwise, the organization may face solvency problems. On the other hand, an organization whose cash and equivalents greatly exceed its current liabilities might not be putting its money to best use.

Fiscal year ending: cloud_download Download Data


Financial trends analysis Glossary & formula definitions

Fiscal Year: Jan 01 - Dec 31

SOURCE: IRS Form 990 info

This snapshot of AFE FOUNDATION’s financial trends applies Nonprofit Finance Fund® analysis to data hosted by GuideStar. While it highlights the data that matter most, remember that context is key – numbers only tell part of any story.

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Business model indicators

Profitability info 2018 2019 2020 2021 2022
Unrestricted surplus (deficit) before depreciation $104,120 $77,672 $96,074 $125,593 $235,878
As % of expenses 96.5% 57.6% 93.3% 87.2% 104.1%
Unrestricted surplus (deficit) after depreciation $104,120 $77,672 $96,074 $125,593 $235,878
As % of expenses 96.5% 57.6% 93.3% 87.2% 104.1%
Revenue composition info
Total revenue (unrestricted & restricted) $212,005 $212,425 $199,039 $269,655 $462,366
Total revenue, % change over prior year 31.7% 0.2% -6.3% 35.5% 71.5%
Program services revenue 0.0% 0.0% 0.0% 0.0% 0.0%
Membership dues 0.0% 0.0% 0.0% 0.0% 0.0%
Investment income 0.9% 3.2% 1.4% 0.7% 0.8%
Government grants 0.0% 0.0% 0.0% 0.0% 0.0%
All other grants and contributions 99.1% 96.8% 97.0% 79.8% 99.2%
Other revenue 0.0% 0.0% 1.5% 19.5% 0.0%
Expense composition info
Total expenses before depreciation $107,885 $134,753 $102,965 $144,062 $226,488
Total expenses, % change over prior year 26.6% 24.9% -23.6% 39.9% 57.2%
Personnel 53.1% 49.0% 58.1% 47.2% 43.3%
Professional fees 1.4% 4.4% 1.7% 16.4% 4.8%
Occupancy 5.0% 3.8% 4.9% 4.0% 2.6%
Interest 0.0% 0.0% 0.0% 1.6% 0.0%
Pass-through 0.0% 0.0% 0.0% 0.0% 0.0%
All other expenses 40.5% 42.7% 35.3% 30.8% 49.3%
Full cost components (estimated) info 2018 2019 2020 2021 2022
Total expenses (after depreciation) $107,885 $134,753 $102,965 $144,062 $226,488
One month of savings $8,990 $11,229 $8,580 $12,005 $18,874
Debt principal payment $0 $0 $0 $0 $0
Fixed asset additions $0 $0 $0 $0 $0
Total full costs (estimated) $116,875 $145,982 $111,545 $156,067 $245,362

Capital structure indicators

Liquidity info 2018 2019 2020 2021 2022
Months of cash 46.6 42.4 76.3 58.7 11.4
Months of cash and investments 46.6 42.4 76.3 58.7 50.8
Months of estimated liquid unrestricted net assets 46.0 43.7 68.4 59.4 50.3
Balance sheet composition info 2018 2019 2020 2021 2022
Cash $418,676 $476,022 $654,384 $704,697 $215,540
Investments $0 $0 $0 $0 $743,044
Receivables $0 $24,037 $15,785 $2,732 $750
Gross land, buildings, equipment (LBE) $0 $0 $0 $0 $0
Accumulated depreciation (as a % of LBE) 0.0% 0.0% 0.0% 0.0% 0.0%
Liabilities (as a % of assets) 1.3% 4.4% 12.4% 1.2% 1.3%
Unrestricted net assets $0 $0 $0 $0 $0
Temporarily restricted net assets $0 N/A N/A N/A N/A
Permanently restricted net assets $0 N/A N/A N/A N/A
Total restricted net assets $0 $0 $0 $0 $0
Total net assets $413,433 $491,105 $587,179 $712,772 $948,650

Key data checks

Key data checks info 2018 2019 2020 2021 2022
Material data errors No No No No No


The people, governance practices, and partners that make the organization tick.

Executive Director

Mrs. Miranda Klassen

Miranda Klassen is the Executive Director of the Amniotic Fluid Embolism Foundation, a non-profit advocacy and research organization she founded in 2008 after surviving a near-fatal AFE during the birth of her son. Miranda also serves as a lead investigator for the Amniotic Fluid Embolism Registry, which she co-founded alongside expert clinicians at Baylor College of Medicine. She serves as the patient advocate for the California Maternal Quality Care Collaborative (CMQCC), Council of Patient Safety in Women’s Health Care, Institute for Perinatal Quality Improvement, and the Maternal Cardiac Arrest Workgroup.

Number of employees

Source: IRS Form 990


Officers, directors, trustees, and key employees

SOURCE: IRS Form 990

Show data for fiscal year
Compensation data
Download up to 5 most recent years of officer and director compensation data for this organization

There are no highest paid employees recorded for this organization.


Board of directors
as of 01/13/2023
SOURCE: Self-reported by organization
Board of directors data
Download the most recent year of board of directors data for this organization
Board co-chair

Amy De Simone

AFE Foundation

Term: 2022 - 2024

Board co-chair

Mrs. Michelle Moon

Visit San Antonio

Term: 2022 - 2024

David Di Pietro


Crystal Matthews

Unified Health Care

Naomi Ventour


Irene A Stafford

University of Texas Health Sciences Center

Stephanie Arnold


Diana Masulli


Board leadership practices

SOURCE: Self-reported by organization

GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section.

  • Board orientation and education
    Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations? Yes
  • CEO oversight
    Has the board conducted a formal, written assessment of the chief executive within the past year ? No
  • Ethics and transparency
    Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year? Yes
  • Board composition
    Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership? Yes
  • Board performance
    Has the board conducted a formal, written self-assessment of its performance within the past three years? Yes

Organizational demographics

SOURCE: Self-reported; last updated 7/20/2022

Who works and leads organizations that serve our diverse communities? Candid partnered with CHANGE Philanthropy on this demographic section.


The organization's leader identifies as:

Race & ethnicity
Gender identity
Female, Not transgender
Sexual orientation
Heterosexual or Straight
Disability status
Person without a disability

Race & ethnicity

Gender identity

Transgender Identity

Sexual orientation